DNA is the code of life.
Specific sequences of DNA encode genes, which serve nearly every function in our bodies. Development, homeostasis, and reproduction; aging, disease, and death—all are driven by the activity of genes.
Small and large errors in genes can cause disease. Thousands of these diseases lack effective or curative treatments today.
The definitive genetic medicines platform.
Gene Writing can make almost every type of genomic alteration—potentially enabling treatments for diseases that aren’t treatable with other genetic medicine technologies.
Gene Writing can write and rewrite DNA at the scales necessary to cure most genetic diseases
1 - 3 BP Substitutions
To fix any single base pair mutation
1 – 100 BP Insertions & deletions
To fix expansion and truncation mutations
100 – 4000 BP Exons
To address many mutations at the same time
1000 BP+ Genes
To address recessive mutations
Remarkable flexibility in delivery modality.
Gene Writer proteins and templates can be delivered via RNA, DNA, or a combination of both, opening new opportunities for genetic medicine.
By taking advantage of existing delivery technologies—like AAV vectors, lipid nanoparticles, or ex vivo cell manipulation—we can choose the best method to deliver Gene Writing technology depending on where it needs to go in the body.
This flexibility means that in the future, we could cure rare genetic disorders with treatments that are easily distributed, manufactured at scale, and re-dosed if necessary.